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Name : Jyotirmayee Dash

Department : School of Chemical Sciences
Designation : Senior Professor
Contact : +91 33 2473 4971 (Ext:1405)
Email : ocjd@iacs.res.in



  


Academic Profile

Professor IACS, since 2018.

Associate Professor, IACS, 2014-2018

Assistant Professor, Indian Association for the Cultivation of Science (IACS), Kolkata, 2012-2014

Assistant Professor,  Indian Institute of Science Education and Research (IISER), Kolkata2009-2012

Research Experience

Visiting Fellow, May-July 2010, University of Bristol, UK

(with Professor Stephen Mann, FRS).

Marie-Curie  Fellow, 2007-2009, University of Cambridge, UK

(Research advisor: Professor Sir Shankar Balasubramanian, FRS).

Postdoctoral Fellow, 2006-2007, ESPCI-Paris, France

(Research advisor: Professor Janine Cossy).

Alexander von Humboldt Fellow, 2004-2006, Freie Universität Berlin, Germany

(Research advisor: Professor Dr. Hans-Ulrich Reissig).

Education

Ph.D. (Synthetic Organic Chemistry), Indian Institute of Technology, Kanpur, India, 2003

(Research advisor: Prof.  F. A. Khan).

M.Sc. (Chemistry), Ravenshaw University, Cuttack, India.


Group

Soumya Jyoti Basak

CSIR-SRF
B.Sc (Chemistry), Malda College, 2017
M.Sc (Chemistry), IIEST SHIBPUR, 2019
Joined lab on July, 2019
basaksoumya09@gmail.com
Nabin Parui

CSIR-SRF
B.Sc (Chemistry), Netaji Mahavidyalaya, Arambagh, 2017
M.Sc (Chemistry), University of Burdwan, 2019
Joined lab on Jan, 2020
nabinparui@gmail.com
Binayak Lala

CSIR-SRF
B.Sc (Chemistry) Jadavpur University, 2017
M.Sc (Organic Chemistry) Jadavpur University, 2019
Joined lab on Oct, 2020
binayaklala@gmail.com
Tathagato Bhattacharyya

CSIR-SRF
Integrated M.Sc (Biotechnology), St. Xavier's College
Joined lab on Oct, 2020
tatha231097@gmail.com
Debasmita Biswas

CSIR-SRF
Integrated M.Sc (Biotechnology), St. Xaviers College
Joined lab on Oct, 2020
debasmita.biswas10@gmail.com
Charles Patriot Roy

CSIR-SRF
B.Sc (Chemistry), St. Paul's Cathedral Mission College, 2017
MS (Chemical Sciences), IISc Bangalore, 2020
Joined lab on Oct, 2020
cscpr2328@iacs.res.in
Sandip Maiti

CSIR-SPMF(Junior)
B.Sc (Chemistry), St. Paul's Cathedral Mission College, 2017
M.Sc (Chemistry), Rajabazar Science College, CU, 2019
Joined lab on Sep, 2021
maitysandip.sm@gmail.com
Sudeshna Mondal

UGC-SRF
B. Sc, Microbiology, Burdwan University, 2017
M. Sc, Biotechnology, Jadavpur University, 2019
Joined lab on Sep, 2021
sudeshnamondal57@gmail.com
Somenath Paul

CSIR-JRF
B.Sc. (Zoology), West Bengal State University, 2016
M.Sc. (Zoology), West Bengal State University, 2018
Joined lab on Mar, 2022
somenathnpaul@gmail.com
Swomi basu

UGC-JRF
BSc. (Biochemistry), Vivekananda College, Calcutta University, 2018
MSc (Chemical and Molecular Biology), IIT Kharagpur, 2020
Joined Lab on Aug, 2022
swomibasu@gmail.com
Pratap Paul

UGC-JRF
B.Sc.(Chemistry), Jadavpur University, Kolkata, 2019
M.Sc.(Chemistry), Jadavpur University, Kolkata, 2021
Joined lab on Aug, 2022
pratap.paul270998@gmail.com
Neha Poddar

JRF
BSc. (Biochemistry), University of Calcutta, 2020
Integrated MS-PhD, IACS, Kolkata, 2022
Joined Lab on Jan, 2023
nehapoddar87680@gmail.com
SK JUBAYAR AHASHAN

UGC-JRF
B.Sc (Chemistry), Presidency University, 2020
M.Sc (Chemistry), IIT ROPAR, 2022
Joined lab on Jan, 2023
scssja2848@iacs.res.in
Kousik Maji


B.Sc (Chemistry), Bankura Christian College, Bankura University, 2021
Integrated MS-PhD, IACS, Kolkata, 2023
Joined Lab on Aug, 2023
kousikmaji178@gmail.com
Manab Diasi

UGC-JRF
B.Sc(Chemistry), Keshpur College, Vidyasagar University,2018
M.Sc (Chemistry), IIT Gandhinagar, 2020
Joined Lab on Jan,2024
diasimanab@gmail.com
Syed Ramizul Kabir

CSIR-JRF
Integrated M.Sc (Chemistry), NISER ,2020
Joined lab on Jan, 2024
syedramizulkabir.srk@gmail.com
Dr. Semantee Bhattacharya

DHR-Women Scientist
M.Sc Biotechnology (Jadavpur University), 2008
PhD Biotechnology (Jadavpur University), 2015
Joined Lab in 2018
scssb1879@iacs.res.in
Dr. Sayantan Pradhan

SERB-RA
PhD Biotechnology (Jadavpur University)
Postdoc DAE - Saha Institute of Nuclear Physics (Chemical Sciences),
CSIR - National Chemical Laboratory (Organic Chemistry Division)
Joined lab in 2023
scssp2875@iacs.res.in
Dr. Joyshree Karmakar

SERB-NPDF
M.Sc (Zoology)- Visva Bharati University, 2010
PhD (Biochemistry)-CSIR-Indian Institute of Chemical Biology, 2021
Joined lab in 2022
joyshreek66@gmail.com
Dr. Amrita Das

DBT-BioCARe Women Scientist
MSc. Zoology (University of Calcutta)
PhD Biochemistry (IICB/ University of Calcutta)
Joined lab in 2024
amritaa.4u@gmail.com


Publication

Publications

134) Efficient Synthesis of Cyclohepta[b]indoles and Cyclohepta[b]indole-Indoline Conjugates via RCM, Hydrogenation, and Acid-Catalyzed Ring Expansion: A Biomimetic Approach

N. Parui, T. Mandal, S. Maiti,  J. Dash*,  Chemistry- A European Journal, 2024 (accepted).

 

133) Combating Multidrug-Resistance in S. pneumoniae: A G-quadruplex Binding Inhibitor of Efflux Pump and its Bio-Orthogonal Assembly, R. Chaudhuri, P. Thumpati, D. Biswas, S. Mandal, J. Dash*, NAR Molecular Medicine, 2024, (accepted).


132) Guanosine-Based Hydrogel as a Supramolecular Scaffold for Template-Assisted Macrocyclization, B. Lala, R. Chaudhuri, T. Prasanth, I. Burkhart, H. Schwalbe, J. Dash*, Chemical Communications, 2024, (accepted).

 

131) pH-Dependent Complex Formation With TAR RNA and DNA: Application Towards Logic Gates, R. Paul, R. Paul,  D. Dutta,  J. Dash*,  Analyst, 2024 (accepted).

 

130) Selective Recognition of c-KIT 1 G-quadruplex by Structural Tuning of Heteroaromatic Scaffolds and Side Chains

K. Fatma, P. Thumpati, D. Panda, V. Ravichandiran, J. Dash*,  ACS Medicinal Chemistry Letters, 2024, (accepted).

 

129)  Total Synthesis of Racemic Benzomalvin E, a Quinazolinone Isolated from Pencilium sp. FN070315 and Exploration to the Direct Synthesis of (E)-Benzomalvin B"

S. Basak, J. Dash*, Journal of Organic Chemistry, 2024, (accepted).

 

128) Potassium tert-Butoxide Mediated Cascade Synthesis of Rutaecarpine Alkaloid Analogs: Access to Molecular Complexity on Multigram Scales" 

S. Basak, J. Dash*, Journal of Organic Chemistry, 2024, 89, 1, 233–244

 

127) Bioorthogonal Chemistry in Translational Research: Advances and Opportunities”

R. Chaudhuri, S. Bhattacharya, J. Dash*, ChemBioChem, 2023, ,24, e20230047


 

126) Nucleoside Derived Metallo-hydrogel Induces Cell Death in Leishmania Parasites,

S. Bhattacharya, T. Bhattacharyya, S.  Khanra, R.  Banerjee, J. Dash*ACS Infectious Diseases, 2023, 9, 9, 1676–1684.

125) KOtBu-Mediated Regioselective Hydroxymethylation of Thiazoles and Benzothiazoles: Synthesis of Biologically Active Heteroaromatic Compounds,

S. Karmakar,  D. Yadav,  J. Dash*Asian J. Org. Chem. 2023  12,   e2023003.


124) "Nucleic Acids as Templates and Catalysts in Chemical Reactions: Target-guided Dynamic Combinatorial Chemistry

and In situ Click Chemistry and DNA/RNA Induced Enantioselective Reactions,

P. Saha, D. Panda, J. Dash*Chemical Society Reviews, 2023, 52, 4248-4291.

123) "Bisindole Enyne as a New Pharmacophore with Anticancer Properties,G. C. Midya, S. Mandal, J. Dash*,

 J. Indian Chem. Soc., 2023,Jul 1;100(7):101028 (invited article).

 

122) "Rapid Access to Substituted Indenones via Grignard Reaction and its Application in the Synthesis of

Fluorenones using Ring Closing Metathesis" 

N. Parui, T. Mandal, J. Dash*European Journal of Organic Chemistry, 2023, 26, e202201285 .

.

121) "Expanding the Toolbox of Target Directed Bio-Orthogonal Synthesis: In Situ Direct Macrocyclization by DNA Templates" 

R.  Chaudhuri, P.Thumpati, J. Dash*Angew. Chem. Int. Ed.. 202210.1002/anie.202215245 and

10.1002/ange.202215245. (front cover, appeared in Hot Topic: Bioorthogonal Chemistry).

 Highlighted in Nature India; https://www.nature.com/articles/d44151-023-00071-7 

 

 

 

120) "Diastereoselective Reversible C-C Bond Exchange of Oxindole-Thiazolidinediones for Dynamic Combinatorial Chemistry"

 A. Gorai, G. Chakraborti,  S. Basak,  J. Dash*Organic & Biomolecular Chemistry202220, 9307-9312.

 

119) "Thiazole Containing PNA Mimic Regulates c-MYC Gene Expression through DNA G-quadruplex" 

A. Gorai, R.  Chaudhuri, T. K. Mukhopadhyay, A. Datta,  J. Dash*Bioconjugate Chemistry 2022, 33, 6, 1145–1155.

 

118) Cycloaddition of N-sulfonyl and N-sulfamoyl azides with alkynes in aqueous media for the

selective synthesis of 1,2,3-triazoles, P.Thumpati, G. Chakraborti, T. Mandal, V. Ravichandiran, J. Dash*

Green Chemistry2022, 24, 911-915.

 

117) Ring closing metathesis for the construction of carbazole and indole-fused natural products

T. Mandal, J. Dash*, Organic & Biomolecular Chemistry, 2021, 19, 9797-9808 (perspective).

 

116) "Triazolyl Dibenzo[a,c]phenazines Stabilize Telomeric G-quadruplex and Inhibit Telomerase",

S. Pal, K. Fatma, V. Ravichandiran, J. Dash*, Asian J. Org. Chem. 2021, 10, 2921-2926.

 

115) "Potassium tert-Butoxide Promoted Synthesis of Dihydroquinazolinones",

T. Ghosh, I. MANDAL, S. Basak,  J. Dash*, J. Org. Chem. 2021, 86, 14695-14704.

Highlighted in SYNFACTS (Synfacts 2022, 10.1055/s-0041-1737738) and Organic Chemistry Portal

(https://www.organic-chemistry.org/abstracts/lit8/187.shtm)

 

 114) "Studies Directed towards the Synthesis of Acridone Family of Natural Products:Total Synthesis of Acronycines and

Atalaphyllidines" T. Mandal, S. Karmakar, A. Kapat, J. Dash*ACS Omega, 2021, 6, 27062-27069.

 

113) A [3+2] Cycloaddition-1,2-Acyl Migration-Hydrolysis Cascade for Regioselective Synthesis of 1,2,3-Triazoles in Water, 

G. Chakraborti, T. Mandal, C. P. Roy, J. Dash*Chemical Communications, 2021, 57, 7970-7973.

 

112) “Binding Insights into Quadruplex Selective Carbazole Ligands”

D Müller, P Saha, D. Panda, J. Dash,* H Schwalbe*, Chemistry–A European Journal, 2021, 27, 12726-12736.

https://doi.org/10.1002/chem.202101866  (Minireview).

 

111) “G4 Sensing Pyridyl-thiazole Polyamide Represses c-KIT Expression in Leukemia Cells”  

R. Paul, D. Dutta, T. Das, M. Debnath, J. Dash*, Chemistry - A European Journal, 2021, 27, 8590-8599. DOI:10.1002/chem.202100907.

 

110) Supramolecular Template Directed In Situ Click Chemistry: A Bio-inspired Approach to Synthesize

G-quadruplex DNA Ligands, T. Bhattacharyya, D. Panda, J. Dash*, Organic Letters2021, 23, 3004-3009.

 

109) Nucleic acid secondary structures for therapeutic and biomolecular device applications

S Bhattacharya, J. Dash*, Chem. Sci. Rep., 2021, (Invited Review Article).

 

108) Prolinamide plays a key role in promoting copper-catalyzed cycloaddition of azides and alkynes in aqueous media

via unprecedented metallacycle intermediates; G. Chakraborti, R. Jana, T. Mandal, A. Datta,* J. Dash*, 

Organic Chemistry Frontiers202182434-2441.

 

107) “Regulation of Gene Expressi