Functional biointerfaces: Sensing, Electron transport and Single molecule structural biology

We are working on Nanoscale Nucleic Acid Sensors where we develop bioactive films of Xeno Nucleic Acids (XNAs) with an aim of achieving better DNA/RNA detection abilities; Nanoscale Biological Electron Transport where we assess the utility of the metalloproteins (human source) as potential molecular bioelectronic components; and Single Molecule level Structural Biology using Scanning Probe Microscopy approach - here we assess the capacity of such an approach by probing the architecture of protein supramolecular assemblies, where the protein structure could be previously unknown, and also by probing the DNA topological changes induced by drug-binding. Click here for a graphical summary of the contributions made in the last few years.

Lab News: Asmita Paul (DBT, JRF) has joined the group for reading PhD in Nanoscale Nucleic Acid Sensing. A Hearty Welcome to Asmita.