MADLAB is involved in tailor made synthesis of metallo-porphyrin complexes and probe, using a combination of spectroscopic techniques and reactivity, fundamental aspects of the heme active sites. In particular, the roles played by the weaker 2^nd sphere interactions in determining the selectivity and, in many cases, the kinetics of the key reactions they catalyze; reactions important for realizing the goal of clean environment and energy in days to come. The group is actively involved in electronic retrosynthesis of complexes with the goal of reducing N₂, CO_x, NO_x and SO_x efficiently and selectively for valorization of industrial waste. Emulating the design principles of metallo-enzymes MADLAB has successfully demonstrated water oxidation, hydrogen evolution and selective reduction of CO₂ to CO under neutral conditions, with 2-20 mA/cm² current density and less than 100 mV overpotential.