Indian Association for the Cultivation of Science

Name : Amit Majumdar

Deptartment : School of Chemical Sciences
Designation : Professor
Contact : + 91 33 2473 4971 (Ext:1165)
Email :


From left: Nabhednu, Anindita, Sayan, Tilak, Ayan, Dr. Amit Majumdar, Tuhin, Manish, Koushik, Jyotiprakash and Tridib.

Research Objectives:

  Our research group has been involved in the area of synthetic inorganic chemistry toward designing of proficient strategies to achieve synthesis and characterization of unusual transition metal complexes, relevant structural-functional model systems for important enzyme active sites and discovering unusual reactivity with a goal to expand the scope of synthetic inorganic chemistry as well as bioinorganic chemistry.

The specific areas of interest include:

  • Reactivity of Nitric oxide with thiol/hydrosulfide in the presence of redox active first row transition metals
  • Functional modeling of flavodiiron nitric oxide reductases, conversion of NO to N2O, mechanistic aspects
  • Non-heme, mono/di-nuclear iron/cobalt complexes
  • Thiolate and hydrosulfide complexes of first row transition metals, selective synthesis and mechanistic aspects

In particular, within the last 9 years we have achieved the following exciting results: (1) nonheme diiron(II) complexes which contain free thiols, (2) dinculear Co(II) complexes which contain only one terminal hydrosulfide, (3) nonheme mononitrosyl diiron complex with [FeII{FeNO}7] formulation which produces N2O upon reduction, (4) desulfurization of thiols, sulfides and thiophenes at room temperature, (5) nonheme diiron(II) and diiron(II, III) complexes with either one/two terminal/bridging hydrosulfide/s, (6) Co(II) and Fe(II) mediated consecutive cleavage of C-S and S-S bond in disulfides, (7) superreduction vs. semireduction mechanism for the conversion of NO to N2O mediated by two functional model complexes of FNORs, (8) isolation of the intermediate that leads to the transition metal mediated C-S bond clevage of thiolates in dinuclear Co(II)/Fe(II)/Ni(II) complexes, (9) syntheis of a unique nonheme monohydrosulfido dinitrosyldiiron complex with [HS{FeNO}7/{FeNO}7] formulation which produces N2O upon reduction, (10) two-electron redox reaction between coordinated thiolates and elemental sulfur to yield trisulfide (S32-) and pentasulfide (S52-chain in binuclear Zn(II) complexes, (11) nitrite induced structural changes in binuclear Mn(II)-thiolate complexes, (12) Co(II) catalyzed hydrolysis of thiolates to alcohols and phenols.

Academic Profile

Academic Profile

Professional Positions:

October 2021 till date: Professor at IACS, Kolkata, India

August 2018 to October 2021: Associate Professor at IACS, Kolkata, India

August 2013 to August 2018: Assistant Professor at IACS, Kolkata, India.

September 2011 to July 2013: Postdoctoral Associate at MIT with Prof. Stephen J. Lippard
February 2009 to August 2011: Postdoctoral Associate at Harvard University with Prof. Richard H. Holm


Ph.D. (2008): Indian Institute of Technology Kanpur, India. (Advisor: Prof. Sabyasachi Sarkar)
M.Sc. (2002): University of Calcutta, India.
B.Sc. (2000): Ramakrishna Mission Residential College, Narendrapur, University of Calcutta, India.


Soumik Karmakar

SRF (CSIR), Joining Date: 01/10/2020
M.Sc.(University of Hyderabad)
Reactivity of thiolates and nitric oxide with first row transition metal complexes
Amit Mandal

JRF(UGC), Joining Date: 01/08/2022
M.Sc. (University of North Bengal)
Transition Metal Thiolates and Nitric Oxide Chemistry
Anuj Baran Chakraborty

SRF (CSIR), Joining Date: 01/10/2020
M.Sc. (University of Calcutta)
Nitric oxide chemistry of first row transition metals
Rahul Saha

Int. PhD Project Student
Int. PhD (Ongoing)
One Year Project on synthesis and reactivity of mononuclear transition meta-thiolate complexes
Sayan Atta

SRF (CSIR), Joining Date: 29/07/2019
M.Sc. (IIT Guwahati)
Nitric oxide reactivity of diiron complexes
Arindam Basak

JRF(UGC), Joining Date: 01/08/2022
M.Sc. (University of Gour Banga)
Transition Metal Thiolates and Nitric Oxide Chemistry
Kamal Hossain

SRF (UGC), Joining Date: 06/01/2020
M.Sc.(University of Kalyani)
Dinuclear transition metal complexes, reactivity with thiolates and nitric oxide




36. "Catalytic Hydrolysis of Thiolates to Alcohols"

       Ganguly, T.; Bera, A.; Chakraborty, A.; Majumdar, A.* Inorg. Chem. 2022, 61, 7377-7386.


35. "Binuclear Manganese(II)-Thiolate Complexes: Synthesis, Characterization and Nitrite Induced Structural Changes"

       Naskar, T.; Jana, M.; Majumdar, A.* J. Mol. Struct. 2022, 1262, 133041.


34. "Polysulfido Chain in Binuclear Zinc(II) Complexes"

       Hossain, K.; Majumdar, A.* Inorg. Chem. 2022, 61, 6295-6310 .


33. "Synthesis, Structural Diversity and Redox Reactions in 1, 2 Bis(diphenylphopshinoethane)Nickel(II)-Thiolate Complexes"

       Pal, N.; Naskar, T.; Majumdar, A.*, Inorg. Chim. Acta. 2022531,120738.


32. "Synthesis and Redox Reactions of Binuclear Zinc(II)-thiolate Complexes with Elemental Sulfur"

       Naskar, T.; Pal, N.; Majumdar, A.*, New. J. Chem. 2021, 4522406-22416.


31. "Reduction of NO by Diiron Complexes in Relation with Flavodiiron Nitric Oxide Reductases"

       Pal, N.; Jana, M.; Majumdar, A.* Chem. Commun. 2021, 57, 8682-8698.

       (Invited Feature Article), Chemical Communications Hot Articles.


30. "A Monohydrosulfidodinitrosyldiiron Complex That Generates N2O as a Model for Flavodiiron Nitric Oxide Reductases: Reaction Mechanism and Electronic Structure"

     Pal, N,; White, C.J.; Demeshko, S.; Meyer, F.; Lehnert, N.;* Majumdar, A.* Inorg. Chem. 2021, 60, 15890-      15900 ("Renaissance in NO Chemistry" special issue).


29. "Thiolate Coordination vs. C-S Bond Cleavage of Thiolates in Dinickel(II) Complexes"

        Das, A.; Ganguly, T.; Majumdar, A.* Inorg. Chem. 2021, 60, 944–958.


28. "Functional Models for the Mono- and Di-nitrosyl Intermediates of FNORs: Semireduction versus Superreduction

      of NO."

  • Jana, M.; 
  • White, C. J.; 
  • Pal, N.; 
  • Demeshko, S.;
  •  Cordes (née Kupper), C.; 
  • Meyer, F.;
  • Lehnert, N.*; 
  • Majumdar, A.
  • *  
  • J.  Am.  Chem. Soc. 2020142, 6600-6616.


27. "Comparative Study for the Cobalt(II) and Iron(II) Mediated Desulfurization of Disulfides Demonstrating That the C-S

      Bond Cleavage Step Precedes the S-S Bond Cleavage Step."

      Ganguly, T.; Majumdar, A.* Inorg. Chem. 2020, 59, 4037-4048.


26. "Iron(II) Mediated Desulfurization of Organosulfur Substrates Produces Nonheme Diiron(II)-hydrosulfides"

       Ganguly, T.; Das, A.; Majumdar, A.* Inorg. Chem.  2019, 58, 9998-10011.


25. "Transfer of Hydrosulfide from Thiols to Iron(II): A Convenient Synthetic Route to Nonheme Diiron(II)-hydrosulfide


Pal, N.; Majumdar, A.* DaltonTrans. (Themed issue: Bioinspired Reactivity and Coordination Chemistry) 2019, 48, 5903-5908.


24. "Cobalt(II) Mediated Desulfurization of Thiophenes, Sulfides and Thiols".

Ganguly, T.; Das, A.; Jana, M.; Majumdar, A.* Inorg. Chem.201857, 11306-11309.


23. C–S Bond Cleavage, Redox Reactions and Dioxygen Activation by Nonheme Dicobalt(II) Complexes

Jana, M.; Majumdar, A.* Inorg. Chem. 2018, 57, 617-632.


22. "Functional Mononitrosyl Diiron(II) Complex Mediates the Reduction of NO to N2O with Relevance for Flavodiiron NO Reductases"

Jana, M.; Pal, N.; White, C. J.; Kupper, C.; Meyer, F.; Lehnert, N.*; Majumdar A.* J. Am. Chem. Soc. 2017, 139, 14380-14383.


21. "Mononuclear Bis(dithiolene) Mo(IV) and W(IV) Complexes with P, P; S, S; O, S and O, O Donor Ligands: A

       Comparative Reactivity Study"

Khatua, S.; Naskar, T.; Nandi, C.; Majumdar, A.* New. J. Chem. 2017, 41, 9769-9783.


20.Model Compounds for Mo-Nitrate Reductases” in "Metalloenzymes in Denitrification: Applications and Environmental Impacts". Royal Society of Chemistry, Metallobiology Series, Eds. Moura, I.; Moura, J. J. G., Co-Eds. Pauleta, S. R.; Maia, L. November, 2016, Chapter 8, p. 170-184.

Majumdar, A.; Sarkar, S.*


19.Cleavage of Carbon-Nitrogen Bond in 1,3,5-tri-tert-butyl-1,3,5-triazacyclohexane by Copper(I) Bromide

Khatua, S.; Majumdar, A.* J. Mol. Struct. 2016, 1120, 267-273.


18.Controlling the Reactivity of Bifunctional Ligands: Carboxylate Bridged Nonheme Diiron(II) Complexes Bearing Free Thiol Groups

Pal, N.; Majumdar, A.* Inorg. Chem. 2016, 55, 3181-3191.


17.Flavodiiron Nitric Oxide Reductases: Recent Developments in the Mechanistic Study and Model Chemistry for the Catalytic Reduction of NO

Khatua, S.; Majumdar, A.* J. Inorg. Biochem. 2015, 142, 145-153.


16.Bioinorganic Modeling Chemistry of Carbon Monoxide Dehydrogenases: Description of Model Complexes, Current Status and Possible Future Scopes

Majumdar, A.* Dalton Trans. 2014, 43, 12135-12145.


15.Structural and Functional Models in Molybdenum and Tungsten Bioinorganic Chemistry: Description of Selected Model Complexes, Present Scenario and Possible Future Scopes

Majumdar, A.* Dalton Trans. 2014, 43, 8990-9003.


14. “Light-induced N2O production from a nonheme iron-nitrosyl dimer”. Jiang, Y.; Hayashi, T.; Matsumura, H.; Do, L. H.; Majumdar, A.; Lippard, S. J.*; Moënne-Loccoz, P.* J. Am. Chem. Soc. 2014, 136, 12524−12527


13. “Versatile Reactivity of a Solvent-Coordinated Diiron(II) Compound: Synthesis and Dioxygen Reactivity of a Mixed Valent FeIIFeIII Species”. Majumdar, A.; Apfel, U.-P.; Jiang,Y.; Moënne-Loccoz, P.; Lippard, S. J.* Inorg. Chem. 2014, 53, 167-181


12. “Mononitrosyl Non-HemeDiiron Complexes: Importance of Iron Oxidation State in Controlling the Extent of Nitrosylation”. Majumdar, A.; Lippard, S. J.* Inorg. Chem. 2013, 52, 13292-13294


11. “Bioinorganic Chemistry of Molybdenum and Tungsten Enzymes: A Structural-Functional Modelling Approach”. Majumdar, A.; Sarkar, S.* Coord. Chem. Rev. 2011, 255, 1039-1054


10. “Comparative Molecular Chemistry of Molybdenum and Tungsten and Its Relation to Hydroxylase and Oxotransferase Enzymes”. Holm, R. H.*; Solomon, E. I.*;

       Majumdar, A.; Tenderholt, A. Coord. Chem. Rev. 2011, 255, 993-1015


9. “Specific Incorporation of Chalcogenide Bridge Atoms in Molybdenum/Tungsten-Iron Sulfur Single Cubane Clusters”. Majumdar, A.; Holm. R. H.* Inorg. Chem. 2011, 50, 11242-11251


8. “Stabilization of 3:1 Site-Differentiated Cubane-Type Clusters in the [Fe4S4]1+ Core Oxidation State by Tertiary Phosphine Ligation: Synthesis, Core Structural Diversity and S = ½ Ground States”. Deng, L.; Majumdar, A.; Lo, W.; Holm. R. H.* Inorg. Chem. 2010, 49, 11118–11126


7. “Reactions of MonodithioleneTungsten(VI) Sulfido Complexes with Copper(I) in Relation to the Structure of the Active Site of Carbon Monoxide Dehydrogenase”.Groysman, S.; Majumdar, A.; Zheng, S-L.; Holm.R. H.* Inorg. Chem. 2010, 49, 1082-1089


6. “Mixed Ligand Tris Chelate Complexes of Molybdenum (IV) and Tungsten (IV): A Comparative Experimental and Theoretical Study”. Majumdar, A.; Sarkar. S.* Inorg. Chim.Acta. 2009, 362, 3493-3501


5. “Necessity of Fine Tuning in Mo(IV) Bis(Dithiolene) Complexes to Warrant Nitrate Reduction”. Majumdar, A.; Pal, K.; Sarkar. S.* Dalton Trans. 2009,1927-1938


4. “Mono-oxo Bis(dithiolene) Mo(IV) / W(IV) Complexes as Building Blocks for Sulfide Bridged Bi and Tri-Nuclear Complexes”. Majumdar, A.; Mitra, J.; Pal, K.; Sarkar. S.* Inorg. Chem. 2008, 47, 5360 – 5364


3. “Selectivity of Thiolate Ligand and Preference of Substrate in Model Reactions of Dissimilatory Nitrate Reductase”.Majumdar, A.; Pal, K.; Sarkar. S.* Inorg. Chem. 2008, 47, 3393 – 3401


2. “Desoxo Molybdenum(IV) and Tungsten(IV) bis(dithiolene) Complexes: Monomer Dimer Interconversion Involving Reversible Thiol Bridge Formation". Majumdar, A.; Pal, K.; Nagarajan, K.; Sarkar , S.* Inorg. Chem. 2007, 46, 6136 – 6147


1. “Chemistry of [Et4N][MoIV(SPh)(PPh3)(mnt)2] as an Analogue of Dissimilatory Nitrate Reductase with its Inactivation on Substitution of Thiolate By Chloride”. Majumdar, A.; Pal, K.; Sarkar. S.* J. Am. Chem. Soc. 2006, 128, 4196 – 4197



Postgraduate Course (previously integrated PhD course):

  • CHS4202 (Revised Course Structure): Main Group and Organometallic Chemistry (Main Group Chemistry, Organometallic Chemistry, Metal Clusters, Modern Interpretation of Electronic Structure and Bonding in Main Group Compounds) 2020 onwards
  • SEC-4200/5200 (Seminar Course): 2019 onwards
  • Laboratory Course (CHS 4105): 2019
  • CHS4202 (Previously CH 423): Chemistry of the Elements (Main Group Chemistry, Inner Transition Elements, Organometallic Chemistry, Inorganic Chains, Rings, Cages and Clusters, Isopoly and Heteropoly Acids, Metal-Metal Bonds and Metal Clusters) 2018-2019
  • CH-423: Inorganic Chemistry-II (Bonding, Spectra and Magnetism of Coordination Compounds, Organometallic Chemistry, Inorganic Chains, Rings and Cages) 2016-2017

PhD Course:

PhD 07: Concepts, Models and Techniques in Chemistry (in 2016)




  • Two Inert Atmosphere Glove Boxes
  • Electrochemical analyzer 
  • UV-Vis Spectrophotometer
  • Three Rotary Evaporators Equipped with Recirculating Chillers and Diaphragm Pumps
  • Recirculating Chiller for Condensers in Fume Hood
  • Low Temperature Reaction Setup
  • Digital Precision Balances
  • Fume Hoods

Extramural Fundings:

  • SERB, IndiaProject File No.: CRG/2022/001931, Title: "Reactivity of Nitric Oxide, Thiolate and Hydrosulfide with Diiron Complexes", Duration: 23/12/2022 onwards, Rs. 42,83,200 (Rs. 32,83,200 from SERB + Rs. 10,00,000 from IACS). ONGOING
  • CSIR, India. Project No. 01(2972)/19/EMR-II, Title: "Nonheme Dinuclear Transition Metal Complexes with Sulfide and Hydrosulfide Ligands", Duration: 05/06/2019 - 04/06/2022, Rs. 14,00,000.  COMPLETED
  • SERB, IndiaProject No.: EMR/2017/000828, Title: "Comparative Reactivity of Nitric Oxide and Thiolates with Dinuclear Transition Metal Complexes", Duration: 18/08/2018 - 17/08/2021, Rs. 34,62,345.  COMPLETED
  • CSIR, India. Project No.: 01(2804)/14/EMR-II, Title: "Activation of Small Molecules Using Non-Heme, Carboxylate Bridged Diiron Complexes", Duration: 01/01/2015-31/12/2017, Fund: Rs. 6,00,000. COMPLETED
  • SERB, India. Project No.: SB/S1/IC-43/2013, Title: "Structural and Functional Models for the Active Sites of Carbon Monoxide Dehydrogenases", Duration: 28/05/2014-27/11/2017, Fund: Rs. 51,00,000. COMPLETED

Open Positions

PhD positions are available. Interested candidates with CSIR/UGC JRF are encouraged to apply.


Project Students Alumni

Past PhD Students
1. Dr. Suman Khatua (13/01/2014-05/03/2019): Thesis Title: "Synthesis and Reactivity of Molybdenum, Tungsten and Copper Complexes with N-, O- and S- donor Ligands". Thesis submitted on: 09/10/2018; Ph.D. Viva-voce completed on 12/06/2019. Current Position: Chemical Assistant at Central Revenues Control Laboratory.                       
2. Dr. Nabhendu Pal (09/09/2014-14/09/2020): Thesis Title: "Reactivity of Dioxygen and Nitric Oxide with Nonheme Diiron(II)-Thiolates/Hydrosulfides". Thesis submitted on: 22/07/2019; Ph.D. Viva-voce completed on 14/09/2020. Current Position: Postdoctoral Associate with Prof. Lawrence Que, Jr. at University of Minnesota, Minneapolis, USA.
3. Dr. Manish Jana (12/06/2015-12/08/2021): Thesis Title: "Functional Modeling Chemistry of Flavodiiron Nitric Oxide Reductases". Thesis submitted on: 09/09/2020. Ph.D, Viva-voce completed on 12/08/2021. Current Position: Postdoctoral Associate with Prof. Marcetta Y. Darensbourg at Texas A&M University, Collage Station, Texas, USA.
4. Dr. Ayan Das (02/09/2016-30/07/2020): Open Thesis Seminar Completed on 05/02/2021.Thesis Title: "Dinuclear Transition Metal Complexes of Thiolates and Hydrosulfides". Thesis submitted on: 23/06/2021. Ph.D. Viva-voce completed on 01/09/2021. Current Position: Assistant Officer, Quality Control at HPCL.                                                               
5. Dr. Tuhin Ganguly (02/09/2016-24/09/2021): Open Thesis Seminar Completed on 18/06/2021. Thesis Title: "Transition Metal Mediated Desulfurization of Organosulfur Substrates". Thesis submitted on: 06/07/2021. Ph.D. Viva-voce completed on 24/09/2021. Current Position: Postdoctoral Associate with Prof. Loi H. Do, University of Houston, USA.
6. Dr. Tilak Naskar (14/12/2015-09/09/2022): Open Thesis Seminar Completed on 30/06/2022. Thesis Title: "Reactivity of Binuclear Transition Metal Complexes with Thiolates and Sulfide". Thesis submitted on: 11/07/2022. Ph.D. Viva-voce completed on 09/09/2022.
Past Research Associates
  • Dr. Manisha Das (SERB NPDF, 03/01/2020 - 02/01/2022) Current Position: Assistant Professor in Midnapore City College.
  • Dr. Koushik Pramanik (RA-1, 31/05/2019 - 31/05/2021)
  • Dr. Mithun Chandra Majee (RA-1, 12/02/2018 - 12/02/2019) Current Position: Assistant Professor in B. B. College, Asansol.
Past Project Students
  • Ms. Suchismita Karmakar (BS-MS, Sem-IV, IACS, Summer Project, May 2022-xxxxxx)
  • Ms. Amina Khatun (M.Sc. Summer Project, Lady Brabourne College, 15th March-24th May, 2022)
  • Ms. Ananya Hati (Int. Ph.D. IACS, One Year Project, 2021-2022)
  • Ms. Asima Maji (Int. Ph.D. IACS, One Year Project, 2020-2021)
  • Ms. Anindita Ghosh (Int. Ph.D. IACS, One Year Project, 2019-2020)
  • Mr. Jyotiprokash Biswas (M.Sc. University of Calcutta, July 2019-March, 2020)
  • Ms. Pallavi Kundu (M.Sc. Summer Project, Central University of Jharkhand, May-July, 2019)
  • Ms. Priyanka Saha (M.Sc. Summer Project, Lady Brabourne College, April-May, 2019)
  • Mr. Shuvajit Ghosh (M.Sc. Summer Project, IIT Hyderabad, May-July, 2018)
  • Ms. Kuheli Dutta (M.Sc. Summer Project, IIT Kanpur, May-July, 2018)
  • Mr. Sudip Baguli (M.Sc. Summer Project, R. K. M. R. C. Narendrapur, March-April, 2018)
  • Ms. Satarupa Das (BS-MS Dual Degree, IISER Kolkata, May-July, 2017)
  • Mr. Monojit Nandi (BS-MS Dual Degree, IISER Bhopal, May-July, 2017)
  • Mr. Anindya Roy (M.Sc. Summer Project, IIT Hyderabad, May-July, 2017)
  • Ms. Anindita Sasmal (M.Sc. Summer Project, Behala College, March-April, 2017)
  • Mr. Chandan Nandi (M.Sc. Summer Project, R. K. M. R. C. Narendrapur, March-April, 2017)
  • Mr. Partha Bhattacharyya (M.Sc. Summer Project, R. K. M. R. C. Narendrapur)
  • Mr. Pallab Modak (Int. Ph.D. IACS, One Year Project)



Invited Lectures in National and International Forums:

11. 10th Asian Biological Inorganic Chemistry Conference (AsBIC10) during 28th November-3rd December, 2022 in Kobe, Japan.

10. Inorganic Chemistry Discussion Meeting  on 15th January, 2020 at IISER Kolkata.

9. Indo-French Symposium on "Small Molecule Activation for Fuels and Commodity Chemicals Production" during

    November 27-29, 2019 at IACS, Kolkata, India.

8. 19th International Conference on Biological Inorganic Chemistry (ICBIC-19) during August 11-16, 2019 in Interlaken,


7. 'Metal ions in Biology' on 24th June, 2019 at St. Xavier's College (Autonomous), Kolkata, India.

6. National Conference on Functional Molecules (NCOFM-2019) on 30th March, 2019 at University of Calcutta, India.

5. 9th Asian Biological Inorganic Chemistry Conference (AsBIC-9) during 9th-14thDecember, 2018 in Singapore.

4. Modern Trends in Inorganic Chemistry (MTIC)-XVII during 11th-14th December, 2017 at Pune, India.

3. In House Symposium at IACS, Kolkata, India in March, 2017.

2. 5th Symposium on Advanced Biological Inorganic Chemsitry (SABIC 2017) during 7th - 11th January, 2017 at Kolkata, India.

1. Indo-French seminar on 'Bio-inorganic Approaches to Current Health Problems' during March 24 - 28, 2014 at Pondicherry University, Pudhucherry, India.



Contact Us


School of Chemical Sciences
Indian Association for the Cultivation of Science
Phone: +91 33 2473 4971 [Ext. 1165]
Fax: +91 33 2473 2805